Findings - MRI reveals a pituitary macroadenoma in the right side of the gland measuring 2.3 x1.6 x 1.4 cm .It enhances less intensely as compared to adjacent normal pituitary parenchyma. The stalk is deviated to the left side. The chiasma and parasellar structures are uninvolved.
Calvarial thickening.
Spade like phalanges.
Heel pad thickening.
Calvarial thickening.
Spade like phalanges.
Heel pad thickening.
Excess secretion of growth hormone (GH) induces gigantism in prepubertal children and acromegaly in adults. Acromegaly arises from GH-secreting pituitary adenomas.
Radiographic studies show the following:
Radiographic studies show the following:
- Increase in length and thickness of the mandible is noted.
- Underbites can be recognized as a result of mandible enlargement.
- Calvaria is thickened.
- Bony ridges and muscle attachments are exaggerated.
- Frontal, mastoid, and ethmoid sinuses are enlarged.
- Ribs are elongated because of proliferation at the cartilage-bone junction.
- Deep barrel chest often is pronounced in long-standing acromegaly as a result of continued costal growth.
- Periosteal growth of the vertebrae occurs, and osteophytic proliferation of the articular margins of joints frequently is recognized.
- Cartilage proliferation of the larynx is noted.
- Cortical thickening and distal tufting are noted.
- Deformities of the skull are noted.